Prof. Pierfausto Seneci

Argomenti del programma: SENECI'S MODULE (3 CFUs) - Chemical genetics in target ID and validation: elucidation of complex diseases mechanisms (cancer, neurodegeneration) using active compounds from phenotypic assays; identification and validation of druggable molecular targets and useful leads - bromodomains/inflammation, kinesin Eg5/cancer; - Natural products (NPs) in biotechnology and drug discovery.

• As to the frontal/Seneci's part, the material presented during the course (20 ppt presentations, saved as pdf files - all shown slides from frontal lessons) is made available to students on the course's MyARIEL site; 20 mp4 pre-recorded…
• As to the laboratory module/Perdicchia, the teacher will provide the notions / material needed to the students before each lab day.

Argomenti del programma: As to the frontal/Seneci's part, the course aims to provide the student with a good knowledge of the main industrial sectors where synthetic organic chemistry is relevant. Some meaningful examples are presented and thoroughly discussed during the theoretical part of the course. Several intermediates and compounds with industrial relevance will be prepared and characterized during the experimental/laboratory module.

• The material presented during the course (21 ppt presentations, saved as pdf files - all shown slides from frontal lessons) is made available to students on the course's MyARIEL site.

Argomenti del programma: The course aims to provide the student with elements to understand and evaluate several modern chemical technologies applied to biotechnological and pharmaceutical processes, meanwhile providing also the basic theoretical notions to understand the nature and the impact of such technologies.